Pathways to chronicity: mechanisms and evolution of persistence
Monday, July 12, 2021
9. Experimental microbiology, microbial pathogenesis & biofilm, 1,5-hour Symposium
9d. Experimental and cellular microbiology
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2349
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10:45 AM
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12:15 PM
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Pathways to chronicity: mechanisms and evolution of persistence
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9. Basic microbiology
9d. Experimental and cellular microbiology
Failure of immune effector mechanisms and antibiotic therapies is a common observation in chronic infections. Mechanisms exploited by bacterial pathogens to circumvent eradication are complex and divers. However, the molecular understanding of persistence is of utmost importance for future development of therapeutic and preventive strategies. This session will provide a detailed update on current concepts and mechanisms behind bacterial immune evasion and the evolution of antibiotic resistance, ultimately resulting in chronic infections.
10:45 AM
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2349-1
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Phase variation as a driver of persistent infections
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K.
Kate
SEIB (Southport)
11:05 AM
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2349-2
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Dynamic modifications of cell wall components govern immune escape in <em>Staphylococcus aureus</em>
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A.
Andreas
PESCHEL (Tübingen)
11:25 AM
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2349-3
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Within host evolution in <em>Staphylococcus epidermidis</em> results in antibiotic tolerance
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A.
Annelies
ZINKERNAGEL (Zurich)
12:05 PM
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2349-4
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Q&A/Discussion
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